Intro to Cell Biology

ENZYMES http://www.biologie.uni-hamburg.de/b-online/library/cat-removed/enzyme_.gif Chemical reactions need help to get started. Ex: A fire needs a match to get it started. http://www.chuckwagondiner.com/art/matches.jpg http://plato.acadiau.ca/COURSES/comm/g5/Fire_Animation.gif ______________ to get a chemical Energy

required reaction _______________ STARTED ACTIVATION ENERGY = ________________________ ACTIVATION ENERGY REACTANTS PRODUCTS Image from: Pearson Education Inc, publishing as Pearson Prentice Hall. All rights reserved

Image from: Pearson Education Inc, publishing as Pearson Prentice Hall. All rights reser CATALYSTS ___________ HELP CHEMICAL FASTER REACTIONS HAPPEN _______________ Catalysts work byDECREASING ____________ the ___________________________to ACTIVATION ENERGY requiredget a chemical reaction started.

ITS LIKE PUSHING A SNOWBALL UP A HILL Once it gets to top . . . it can roll back all by itself http://www.gifs.net Image from: http://www.hillstrath.on.ca/moffatt/bio3a/digestive/enzanim.htm CATALYSTS in Living Things In living systems PROTEINS __________

that act as catalysts ________________to control chemical reactions are called ENZYMES = _________ SEE ANIMATION of AMYLASE More about this in Chapters 7,8,9 and 12 PROTEINS CAN BE ENZYMES ENZYME

ACTIVE SITE SUBSTRATE ENZYME-SUBSTRATE COMPLEX ENZYME Unchanged & Reusable Image modified from: http://www.biologie.uni-hamburg.de/b-online/library/cat-removed/enzyme_.gif Arrow: http://www.gifanimations.com/action/ImageDisplay/1/2/11/next

PRODUCTS FIT ENZYMES _____ like LOCK AND KEY a _______________ SUBSTRATE ONE KIND to only _________of _________. UNCHANGED Enzymes are ___________ by the

REUSABLE reaction and ___________ http://www.grand-illusions.com/images/articles/toyshop/trick_lock/mainimage.jpg FACTORS THAT AFFECT ENZYME ACTIVITY temperature pH __________ & ______________ Conditions that are TOO ACIDIC or

TOO HOT cause proteins to UNWIND DENATURE ________ or _________ See a movie Choose narrated http://www.desktopfotos.de/Downloads/melt_cd.jpg http://www.nealbrownstudio.com/adm/photo/163_nb_fried_egg.jpg Denaturing _______ the shape _______ of the

changes ACTIVE SITE ______________ so enzyme SUBSTRATE ______________ to ____________ CANT BIND _______________ (keeping pH and HOMEOSTASIS temperature constant) isIMPORTANT ______________

ENZYME FUNCTION for maintaining ____________________ Image modified from: http://www.lewport.wnyric.org/jwanamaker/animations/Enzyme%20activity.html Many enzyme NAMES end -ASE in _____ and the beginning of the name tells what it does DNA Polymerase= polymerizes

joins monomers to make DNA Protease= breaks down proteins MAKE CONNECTIONS How is the SHAPE of an enzyme related to its FUNCTION? ://www.gb-sports.co.uk/zoggsfinz.jpg ://www.webweaver.nu/clipart/img/misc/construction/hammer-animation.gif

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