Medical Treatment of Benign Prostatic Hyperplasia - ymf.org.tw

Medical Treatment of Benign Prostatic Hyperplasia - ymf.org.tw

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Normal men1 Late menopausal women1 Early menopausal women1

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Bone marrow transplant3 4.6% Androgen-deprivation therapy4 7.0% AI therapy plus GnRH agonist5 Ovarian failure

secondary to chemotherapy6 7.7% 0 2 4 6 8 Lumbar spine BMD loss at 1 year, %

AI; aromatase inhibitor; GnRH, g)onadotropin-releasing) hormone; PMW, postmenopausal women. 1. Kanis JA. In: Osteoporosis. Blackwell Healthcare Communications Ltd, 1997; 2. Eastell R, et al. J Bone Miner Res. 2006;21(remodeling)8):1215-1223; 3. Lee WY, et al. J Clin Endocrinol Metab. 2002;87(remodeling)1):329-335; 4. Maillefert JF, et al. J Urol. 1999;161(remodeling)4):1219-1222; 5. Gnant M, et al. Breast Cancer Res Treat. 2002;76(remodeling)suppl 1):S31. Abstract 12; 6. Shapiro CL, et al. J Clin Oncol. 2001;19(remodeling)14):3306-3311.

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(remodeling)BMD < -2.5 SD) Osteopenia Osteoporosis Severe osteoporosis 2.5

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