AAALAC International History, Programs and Process What is
AAALAC International History, Programs and Process What is AAALAC? AAALAC stands for the Association for Assessment and Accreditation of Laboratory Animal Care International. The mission: AAALAC International enhances life sciences by
promoting the responsible treatment of animals used in research, teaching and testing through voluntary accreditation and assessment programs. Origins During the post-World War II science boom, leading veterinarians and researchers saw the need for an independent organization to encourage high standards for humane animal care and use in science.
AAALAC was created to meet this need, and was incorporated as an independent nonprofit organization in 1965. Growth AAALAC accredits universities, companies, government agencies, and nonprofit organizations. In 1996, AAALAC changed its name to include
International in order to reflect its growth outside the United States. Today, more than 880 companies, universities, hospitals, government agencies and other research institutions in 37 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. AAALAC now has offices in Rockville, Maryland (USA), Brussels, Belgium, and Waikoloa, Hawaii.
International representation AAALAC has a multinational Board of Trustees, including representation from ICLAS and FELASA. Accredited organizations in 28 countries including: Austria, Belgium, Canada, Denmark, Egypt, England, France, Germany, Hong Kong, Hungary, India, Indonesia, Italy, Japan, Korea, Mauritius, Norway, Peru, Philippines, Russia, Scotland, South Africa, Spain, Switzerland, Taiwan, Thailand, The
Netherlands, and the United States. Organization 68 Member Organizations govern AAALAC, and are represented on the Board of Trustees. The over 55-member Council on Accreditation carries out the accreditation program.
The Council is comprised of North American, European and Pacific Rim sections which evaluate programs in their respective regions. 330+ ad hoc Consultants help conduct program evaluations. Accreditation
Is completely voluntary and confidential. Is performance-based. Is a peer-review process. Standards Guide for the Care and Use
of Laboratory Animals (NRC 2011) Guide for the Care and Use of Agricultural Animals in Research and Teaching European Convention for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes, Council of Europe;(ETS 123)
Other widely accepted guidelines The process AAALAC accredits the entire program which includes:
animal care and use policies and responsibilities animal environment, housing and management veterinary medical care physical plant Maintaining accreditation Submit an annual program report to AAALAC. (The annual report form is mailed to you.)
Be revisited and re-evaluated once every three years. Major program changes or deficiencies must be reported to AAALAC in between site visits. Accreditation
Provides a confidential, third-party peer review. Promotes scientific validity. Represents quality. Demonstrates accountability. Assures funding sources. Helps recruit quality people. Shows a real commitment to humane animal care. What people value most about accreditation
It assures the credibility of our program among funding sources. It provides the public with a positive image. It helps convince management of the need to commit resources
to maintain a high-quality program. What people value most about accreditation It conveys a high level of professionalism to the scientific community. Application of AAALAC standards ensures high-quality research and animal care, resulting in better science.
Completing the Program Description helps us identify weaknesses and self-correct them. What people value most about accreditation It assures our customers that we have a quality program.
The rigorous peer-review evaluation ensures that were doing things right. Accreditation also entitles you to: Receive AAALACs proprietary electronic newsletter, the AAALAC E-brief. A free subscription to AAALACs Connection newsletter.
Telephone and e-mail consultations. Accreditation also entitles you to: Listing in the online AAALAC Directory of Accredited Programs. Access to AAALACs Members Only Web site:
Materials to promote your accreditation Keeping Connected (a compilation of news articles and meeting announcements of interest to the animal care community)
Tools for maintaining your accreditation Periodic updates on the accreditation program and animal care and use issues. Maintaining standards of animal care and use Getting it right Role of the IACUC
Protocol Review Program Review Facilities and Use Area Review Address animal concerns Note: The IACUC is required to conduct the same level of review twice per year as the AAALAC Int. Program review team conducts every three years. IACUC Protocol
Know your animal protocol. Match to your grant application. Refer to the protocol often. Make no deviations from the protocol. There is no such thing as a pilot study that does not need IACUC approval. Has everyone in the lab read the protocol and
know where it is located? Training Prior to Work With Animals Training for research staff IACUC-required training includes RPF Modules,
species specific training, and all required EHS training Hands on training by PI or designated staff member Training for animal care staff Required IACUC and EHS training Documented on-the-job training Certification by AALAS is ideal
Where would you expect better study results from ? Here? Or Here? First Impressions Keep laboratory neat and organized This says a great deal about the lab Convey image that animal users are interested in a quality program Good Animal Care = Good Science
Storing Equipment & Supplies http://healthcare.spacesaver.com/centralsterile.jpg Signage Animal related injury procedures Emergency vet care Rodent Survival Surgery
Reporting Concerns (animal welfare) Rodent Aseptic Surgery Must follow University of Pittsburgh published Guidelines Appropriate sterilization of instruments
Surgical preparation of animal and surgeon Monitor anesthesia An anesthetized animal can not be left unattended Post-Operative Care consistent with University of Pittsburgh Guidelines And as described in your protocol Inhalant Anesthesia Use Use anesthetics only as described in the protocol.
Gas anesthetic vaporizers should be calibrated at least every 2 years. See policy at www.iacuc.pitt.edu. Use a chemical fume hood or other means to scavenge gas anesthetic agents appropriately. Documenting Procedures Blue Procedure Cards
Research Records Dates, procedures, observations, initials http://www.bedfordlabs.com/BedfordLabsWeb/products Animal Health Issues?
Post-procedure complications. What do you do? What do you do with a sick animal on the weekend? Do you know the point at which the animal should be euthanized? What does the protocol state? Remember: ALL clinical care of animals MUST be coordinated through the Division of Laboratory Animal Resources (DLAR). Can you name a University Veterinarian or Vet Technician? Clinical Records for Warm-blooded Species Other Than Rodents
Each animal must have an individual clinical record A post-procedure form (http://www.iacuc.pitt.edu) must be completed for every procedure done on the animal, as well as for euthanasia. For animals other than rodents, vital signs must be recorded at least every 15 minutes during surgery (including non-survival surgeries) on an anesthetic monitoring form (http://www.iacuc.pitt.edu ) Clinical Records for Warm-blooded
Species Other Than Rodents Completed clinical records must be turned in to DLAR Veterinary Services Active clinical records must be maintained in the animal housing room or procedure area All drugs administered to an animal must be entered into its clinical record Writing Legibly DRUGS
Only use those drugs listed in the protocol Other drugs that may be needed for clinical care must be under the direction of a veterinarian Do you have a system for identifying and disposing of expired drugs? Controlled substances will be audited. Know the DEA laws!!
All chemical containers must be labeled See IACUC Policy on Secondary Labeling An expiration date must be on the label of all drug containers Keep chemicals away from human or animal food items Garbing Properly http://www.inmagine.com/searchterms/surgical_gloves.html
http://www.mdp-miami.com/catalog/images/masksnmore Occupational Health and Safety All animal users MUST be enrolled in the Animal Exposure Surveillance Program (AESP) Physical Issues: Do not recap needles- see EHS policy
Bite wounds- do you know what to do? See animal related injury guidelines Personal Protective Equipment- do you know what is required? Certifications
Gas anesthetic vaporizers and anesthetic machines must be maintained and certified at least every two years Fume hoods and Biological Safety Cabinets must be certified annually Animal transport
Use only Approved transport routes No public elevators Use only DLAR approved transport devices Visitors Policy Visitors to your lab need to obtain permission from the DLAR Clinical Director prior to their visit. To initiate permission to have a visitor, contact the DLAR at 412-648-8950. Animal Housing
According to the Guide, no overcrowding is permitted Identification
Review size requirements listed in the Guide for the Care and Use of Laboratory Animals for proper caging. Delayed or incomplete weaning is the most common cause of overcrowded conditions Cage cards must be visible and information completed Animals must be identified No housing of animals outside of the designated animal facility space is permitted unless approved by the IACUC Euthanasia AVMA Guidelines on Euthanasia - 2013
https://www.avma.org/KB/Policies/Documents/euthanasia.p What methods do you use to ensure death? Your euthanasia procedure must be performed as written in your University of Pittsburgh protocol Physical methods of euthanasia require specialized training and justification Use of a guillotine for euthanasia requires that it be
properly maintained. University of Pittsburgh Policies Designed to help users and the University of Pittsburgh to maintain a program consistent with the Guide for the Care and Use of Animals Posted on the University of Pittsburgh IACUC website, www.iacuc.pitt.edu
If you need clarification or assistance, contact the IACUC office at 412-383-2008 Animal Welfare or Compliance Concerns What can you do? https://www.iacuc.pitt.edu/about/report-concerns Animal Care Acronyms to Know AAALAC-Int.-Association for the Assessment and
Accreditation of Laboratory Animal Care-International IACUC-Institutional Animal Care and Use Committee USDA-United States Department of Agriculture AWA-Animal Welfare Act
OLAW-Office for Laboratory Animal Welfare AALASAmerican Association of Laboratory Animal Science The Information Super Highway www.dlar.pitt.edu http://cme.hs.pitt.edu www.iacuc.pitt.edu www.ibc.pitt.edu www.rcco.pitt.edu www.ehs.pitt.edu www.AAALAC.org Please contact us if you have any questions
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