TRIBE TRANSLATIONAL RESEARCH IN BIOMEDICINE WHAT IS GRADUATE

TRIBE TRANSLATIONAL RESEARCH IN BIOMEDICINE WHAT IS GRADUATE

TRIBE TRANSLATIONAL RESEARCH IN BIOMEDICINE WHAT IS GRADUATE SCHOOL? It is founded by joining several graduate studies in order to increase research and teaching capacities, to harmonize the criteria, to encourage interdisciplinary approach and better economic organization and implementation of graduate studies. PROBLEMS OF PhD COURSES - Low success rates - Unregulated relationship between school and PhD courses - Mismatch between existing

programs - Diversity of scientific profiles OUR PRINCIPLES - Emphasize on intensive work with students and not on formal teaching - Continuous monitoring of students and their mentors - Interdisciplinary approach NEWS Teaching at graduate studies is not edditionaly paid. School employees are not paying for the postgraduate study. AIM - Increase number and quality of publications related to PhD thesis

- Internationally acclaimed program - 100% success rate TRIBE ECTS system 1. godina - PREDMETI Kod Naziv predmeta Nastava P + S +V ECTS ZOP1 PT001 PT-ZOP1 Uvod u znanstveni rad (prof.dr.sc. Matko Marui)

6+6+0 2 ZOP2 PT002 PT-ZOP2 Opa biostatistika (doc.dr.sc. Ozren Polaek) 4+4+8 2 ZOP3 PT003 PT-ZOP3 Pisanje znanstvenog lanka

(doc.dr.sc. Livia Puljak) 10+4+10 3 ZOP4 PT004 PT-ZOP4 Izrada plana istraivanja (prof.dr.sc. Matko Marui) 0+20+0 3 ZOP5 PT005 PT-ZOP5

Pisanje znanstvenih projekata (prof.dr.sc. Ivica Grkovi) 2+13+0 2 ZOP6 PT006 PT-ZOP6 Procjena vrijednosti znanstvenog lanka (doc. dr. sc. Livia Puljak) 8+8+0 2 ZOP7 PT007 PT-ZOP7

Etika u istraivanjima (prof.dr.sc. Ana Marui) 6+0+4 2 ZOP8 PT008 PT-ZOP8 Pretraivanje medicinskih informacija (prof.dr.sc. Damir Sapunar) 2+6+6 2 OP1

PT009 PT-OP1 Organizacija i sigurnost laboratorijskog rada (prof.dr.sc. Damir Sapunar) 8+6+4 3 OP2 PT010 PT-OP2 Pokusne ivotinje i ivotinjski modeli (dr.sc. Natalija Filipovi) 10+4+4 3

OP3 PT011 PT-OP3 Metode molekularne i stanine biologije (prof.dr.sc. Maja Pavela Vrani) 4+4+6 2 OP4 PT012 PT-OP4 Poduzetnitvo i transfer tehnologija (prof.dr.sc. Mile elalija) 10+10+5 3

BS26 PT024 PT-IP11 Komunikacijske i prezentacijske vjetine (doc.dr.sc. Livia Puljak) P8+6V 2 30 2. godina IZBORNI PREDMETI TRIBE STUDIJA Kod Naziv predmeta

Nastava PT014 PT-IP1 Zagonetka boli P10+S4 ECTS 2 BS02 Istraivanja ljudskih embrija: etiki, metodoloki i razvojni principi P6+S4+V4 2

BS03 Glikobiologija hematopoeze P2+S4+V10 2 BS04 Glikobiologija imunolokog sustava P4+S6+V5 2 BS05 Molekularne interakcije organskih sustava: osteoimunologija

P3+S5+V7 2 PT015 PT-IP2 Avanture osjeta boli u mozgu P10+S6 2 BS07 Genetike osnove kompleksnih bolesti P4+S5+V6

2 PT016 PT-IP3 Gledanje nevidljivog P10+V6 2 PT018 PT-IP5 Razvoj spinalnih ganglija ovjeka P6+S4+V4 2 BS10

Kopljaa Model za evoluciju Chordata P5+S5+V5 2 BS11 Osnove srane elektrofiziologije i bioenergetike P3+S5+V7 2 BS12 Rak debelog crijeva

P4+S6+V5 2 PT019 PT-IP6 Genetika statistika i genomske baze podataka P4+S4+V4 2 PT020 PT-IP7 Plasticitet neurokemijskog fenotipa P6+S2+V4 2

PT021 PT-IP8 Dijagnostika genskih i kromosomskih poremeaja P7+S4+V4 2 BS16 Oksidativni stres i mehanizmi zatiteuloga mokrane kiseline P6+S4+V5 2 BS17

Multivarijantna statistika P4+S6+V4 2 BS18 Zato i kako diemo? P6+S5+V14 2 BS19 ivotinjski modeli u istraivanju modanog udara P6+S4+V4

2 BS20 Kvazieksperimentalne i neeksperimentalne metode istraivanja P10+S10 2 BS21 Komunikacije u ivim organizmima P6+S4+V4 2

BS22 Uloga ubikvitina i autofagije u zdravlju i bolesti P4+S6+V5 2 BS23 Koncepti medicinske genetike P3+S5+V7 2 PT022 PT-IP9 Translacijska istraivanja sluanja i govora

P10+S6+V4 2 PT023 PT-IP10 Cochrane knjinica i dokazi u medicini P5+5S+5V 2 PT013 PT-OP5 Metode izolacije bioaktivnih tvari 10+6+0

2 PT-IP13 Drug discovery 5+10+0 2 Preoperativno i intraoperativno mapiranje elokventnih regija kore mozga 6+4+4 2 Extracurricular activities List of required extracurricular activities and the corresponding number of ECTS: - Dva rada objavljena u asopisu indeksiranom u CC-u s imbenikom odjeka viim od 1. Pristupnik

mora biti prvi autor na oba rada (15 ECTS bodova). Jedan rad mora biti izravno povezan s temom doktorskog rada. - Two papers published in journals indexed in CC with an impact factor above 1. At least one of these two papers must be related directly to the PhD thesis proposal (15 ECTS per paper). - Tri annual reports on mentor (supervisor) and candidate progress presented and accepted on the Council meeting (3 ECTS). - Tri godinja izvjea o napretku mentora i pristupnika prezentirana i prihvaena na Vijeu (5 ECTS bodova, ukupno 15 ECTS bodova). - At least 3 presentations / seminars (journal club) (3 ECTS total). - At least 3 presentations / seminars on subject related to research in which the graduate student is involved (3 ECTS total). Some of the extracurricular activities and their ECTS: - Dodatni znanstveni rad objavljen u asopisu indeksiranom u CC-u (prvo autorstvo 10 ECTS bodova, koautorstvo 5 ECTS bodova) - Sudjelovanje na meunarodnom kongresu (kongresno priopenje): usmeno izlaganje (3 ECTS boda), poster prezentacija (1 ECTS boda). - Sudjelovanje na domaem kongresu (kongresno priopenje): usmeno izlaganje (1 ECTS bod), poster prezentacija (0.5 ECTS boda).

- Sudjelovanje na domaim, domaim s meunarodnim sudjelovanje, ili meunarodnim znanstvenim seminarima, teajevima, konferencijama, ljetnim kolama i sl. (0.2 5 ECTS boda). - Pohaanje predavanja i seminara koje organizira Ured za znanost (0.5 ECTS boda predava, 0.2 ECTS boda slua) Mentor The PhD and Specialist thesis mentor (supervisor) is a teacher or a researcher holding a research and teaching rank or research rank respectively. At the time of appointment, the mentors (supervisors) must have scientific achievements in the last five years which include at least three papers from the corresponding research field published in journals indexed in Current Contents (CC). With the aim of ensuring the quality of final thesis, the supervision can be granted to researchers outside the School who sign an Agreement of Cooperation and Responsibilities. Taylor M. Reform the PhD system or close it down. Nature 472, 261 (2011) In many fields, it creates only a cruel fantasy of future employment that promotes the self-interest of faculty members at the expense of students. The reality is that there are

very few jobs for people who might have spent up to 12 years on their degrees. But in far too many cases, specialization has led to areas of research so narrow that they are of interest only to other people working in the same fields, subfields or sub-subfields. Education: The PhD factory Cyranoski D. et al. Nature 472, 276-279 (20 April 2011) Career patterns in bioscience research Tournament model - Equal chances of winning a prize - Turning small differences in productivity in huge differences in recognition and awards - High competitiveness To facilitate change, universities should move away from excessive competition fuelled by pernicious rating systems, and develop structures and procedures that foster cooperation. This would enable them to share faculty members, students and resources, and to efficiently

increase educational opportunities. Institutions wouldnt need a department in every field, and could outsource some subjects. Teleconferencing and the Internet mean that cooperation is no longer limited by physical proximity. The EU will need to create at least 1 M new research jobs in order to reach R&D intensity of 3%. The net increase by two thirds of the number of EU researchers by 2020 should primariliy benefit the bussines sector. Christian de Duve The Nobel Prize in Physiology or Medicine 1974 Using simple logic: application presupposes discovery, and discovery requires research, and research implies exploring the unknown, with, by definition, the inability to predict how useful or profitable whatever will be found could turn out to be. Science is one field of human endeavor that must be unashamedly elitist. You cannot

seek the truth with poor thinking or sloppy techniques. In conducting your research, observe total rigour and intellectual honesty in the analysis of facts, consider all possible hypotheses, plan your approach to test those hypotheses, and submit your conclusions to the verdict of observation and experimentation without preconceived ideas. Never conduct research with the aim of proving a theory, but, rather, to invalidate it if it should be wrong. The best proof is failure to disprove. Aside from as a Nobel laureate, how do you want the world to be remember you? I have no such ambition. In the history of science, my contributions are minor and would have been made by someone else had I not stumbled on them first. George Smoot Nobel Prize 2006 in Physics Biological systems are so complex and so poorly observed and measured that biologists had to be satisfied by a high level and rough understanding of what they were studying, while physicists are trained for rigor and precision. Aside from as a Nobel laureate, how do you want the world to remember you? I do not think the world will remember any of us. When you work in cosmology, you

think with a perspective of billions of years. How many people do we remember from 1,000 years ago? How many from 10,000 years ago? How many from 1 million years ago? etc. So now the question is more like that about Ozymandias [from Percy Shelleys poem]. After a thousand or so years nothing is left of the great works but a few broken relics. What will be left in a billion years? The point is not about being remembered or about doing science to win a Nobel prize you do science because you want to be a scientist. Likewise, you live your life in a way you think is good and good for you. Critical thinking Skills and competencies needed in the research field Objectives 2020 Questionnaire: Are you the Ideal Researcher? In this exercise, we are testing for the key essential qualities. Rate your skills on a 3-point scale 0 points - What skill? Ive never thought about this before. 1 point - Its occasionally been known to happen.

2 points - Im an expert at this. A. Scientific Skills A1. My computer and I are inseparable. It does exactly what I ask of it and I can even repair it. Ive also tweaked programme codes. I can relate to my computer. A2. I have talked to researchers from other disciplines about more than just the weather. 0 points - What skill? Ive never thought about this before. 1 point - Its occasionally been known to happen. 2 points - Im an expert at this. B. Management Skills B1. I can ask other researchers if theyd like to interact with me and find common ground for research. B2. I know how much lab supplies cost. I have a system for purchasing lab products at the best price, thereby maximizing the labs limited funding resources. I even know where to exchange our surplus with other labs if

needed. B3. I recognize that scientific experiments are only one tiny part of a huge process that requires me to go around asking for money, work out how to spend it and finally claim to have spent it well before asking for more money again. B4. At social gatherings with non-scientists, I can explain why my research is important for them, their children and their childrens children, although I rarely do this anymore because people stop talking to me. 0 points - What skill? Ive never thought about this before. 1 point - Its occasionally been known to happen. 2 points - Im an expert at this. C. Personal Qualities C1. I am bubbling over with new ideas. C2. I have difficulty sleeping at night whilst preoccupied with the search for novel solutions to experimental problems. I frequently doodle my flashes of inspiration in my lab book and on envelopes, beer mats, tax returns, etc. C3. I often hum, whistle or tap rhythmically in the lab.

0 points - What skill? Ive never thought about this before. 1 point - Its occasionally been known to happen. 2 points - Im an expert at this. Literature Reform the PhD system or close it down Mark Taylor Nature 472, 261-261 (20 April 2011) Education: The PhD factory David Cyranoski, Natasha Gilbert, Heidi Ledford, Anjali Nayar, Mohammed Yahia Nature 472, 276-279 (20 April 2011) Reform the PhD system or close it down Mark Taylor Nature 472, 261-261 (20 April 2011) Education: The PhD factory David Cyranoski, Natasha Gilbert, Heidi Ledford, Anjali Nayar, Mohammed Yahia Nature 472, 276-279 (20 April 2011) Seven ages of the PhD

Raymond Gosling, Cheryll Tickle, Steve W. Running, Yao Tandong, Andras Dinnyes, A. A. Osowole, Erika Cule Nature 472, 283-286 (20 April 2011) Tools http://graduate-school.phds.org/ http://sites.nationalacademies.org/PGA/Resdoc/index.htm

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