Trilogy - cdnmedia.endeavorsuite.com

Trilogy - cdnmedia.endeavorsuite.com

versatility Xpanded Trilogy Series mixed-mode ventilators versatility Xpanded Were expanding the versatility of our Trilogy Series mixed-mode ventilators Expanding ventilatory support Expanding volume targeting Expanding clinical control Confidential Sector, MMMM dd, yyyy, Reference

2 Expanding ventilatory support Mouthpiece ventilation (MPV) Increased pressure support to 40 cm H2O Confidential Sector, MMMM dd, yyyy, Reference 3 Expanding ventilatory support

Mouthpiece ventilation (MPV) MPV is a form of volume ventilation whereby the patients normal state is disconnected from the ventilator and the patient initiates a breath, as needed, through an oral interface. Confidential Sector, MMMM dd, yyyy, Reference 4 What type of patient could benefit from MPV? Conditions with respiratory muscle dysfunction

Muscular dystrophies ALS Other myopathies: acid maltase deficiency, polymyositis, mitochondrial disorders Neurological disorders: spinal muscular atrophies (SMA l,ll,lll) Neuropathies: Guillain-Barre syndrome, multiple sclerosis Skeletal pathologies such as kyphoscoliosis, rigid spine syndrome Confidential Sector, MMMM dd, yyyy, Reference

5 Traditional neuromuscular disease clinical pathway Dx NIV night Dx NIV night

Confidential NIV day and night NIV night Sector, MMMM dd, yyyy, Reference Trach MPV day

6 Which would patients choose? Confidential Sector, MMMM dd, yyyy, Reference 7 Why isnt MPV more widely utilized? Familiarity with current trends in NIV therapy Existing vents require significant

modification Perceived risk and anxiety about the modifications Confidential Sector, MMMM dd, yyyy, Reference 8 What is the risk of using Trilogys MPV feature The MPV feature represents no more risk than any other form of NIV MPV may be used an entire lifetime by some neuromuscular

patients and may extend the quality of life for patients who will eventually need invasive ventilation Confidential Sector, MMMM dd, yyyy, Reference 9 Kiss trigger and MPV support system A new kiss trigger with signal flow technology detects when the patient engages and disengages from the mouthpiece to deliver on-demand ventilation

This feature combines with a mouthpiece ventilation (MPV) support system to enhance ease of use Confidential Sector, MMMM dd, yyyy, Reference 10 PN 1102866 MPV disposable circuit 10 pk Each circuit kit contains two mouthpiece options, the

angled mouthpiece and a straw, and all of the necessary adapters for each The mini flex tube is optional; it should be in place for patients who appreciate the added comfort, but removed for patients that have extremely limited mobility of the head Confidential Sector, MMMM dd, yyyy, Reference

11 PN 1102862 MPV support system Each support system kit contains an assembled clamp and 2 ft. bendable tube holder, and one MPV disposable circuit The clamp can be modified for rail or flat mounting Confidential Sector, MMMM dd, yyyy, Reference 12

Expanding ventilatory support Trilogy Series mixed-mode ventilators are lightweight, versatile and easy to use. The addition of MPV is a unique upgrade that offers an opportunity to improve the quality of life for patients and the possibility of increasing the time before a tracheostomy becomes a patients only option.

Confidential Sector, MMMM dd, yyyy, Reference 13 Increased pressure support (PS) Pressure support is increased to 40 cm H2O Confidential Sector, MMMM dd, yyyy, Reference 14

versatility Xpanded Were expanding the versatility of our Trilogy Series mixed-mode ventilators Expanding ventilatory support Expanding volume targeting Expanding clinical control Confidential Sector, MMMM dd, yyyy, Reference 15

Expanding volume targeting AVAPS-AE Adjustable AVAPS Confidential Sector, MMMM dd, yyyy, Reference 16 AVAPS-AE AVAPS-AE is a auto-titration mode of noninvasive ventilation designed to better treat respiratory insufficiency patients (OHS, COPD and NMD) in

the hospital and homecare environments Achieving a targeted volume is now completely automatic Proven performance of AVAPS Auto EPAP Auto backup rate Confidential Sector, MMMM dd, yyyy, Reference 17 AVAPS-AE Auto EPAP maintains patent upper airway at a comfortable pressure

Auto adjusting EPAP to meet changing patient needs Maintains a patent airway Confidential Sector, MMMM dd, yyyy, Reference 18 AVAPS-AE Auto Back-up rate Auto backup rate provides comfortable assistance when needed Auto backup rate is near resting rate

No manual adjustments (auto-default setting) Confidential Sector, MMMM dd, yyyy, Reference 19 Adjustable AVAPS Adjustable AVAPS allows you to adjust the maximum rate at which the pressure support automatically changes to achieve the target tidal volume It can be set from 1 cm H2O per minute to 5 cm H2O

per minute Allows clinician to customize the setting to the patients needs Confidential Sector, MMMM dd, yyyy, Reference 20 versatility Xpanded Were expanding the versatility of our Trilogy Series mixed-mode ventilators Expanding ventilatory support

Expanding volume targeting Expanding clinical control Confidential Sector, MMMM dd, yyyy, Reference 21 Expanding clinical control On-screen waveforms Sensitive Auto-Trak Confidential

Sector, MMMM dd, yyyy, Reference 22 On-screen waveforms allow clinicians to visually identify Triggering Cycling Synchrony Confidential Sector, MMMM dd, yyyy, Reference

23 Sensitive Auto-Trak Provides an enhanced triggering response for patients with minimal respiratory effort Digital Auto-Trak requires 6 cc of volume change to initiate a breath Sensitive Auto-Trak requires 3 cc Inhale Exhale TIME

Confidential Sector, MMMM dd, yyyy, Reference 24 Additional features In-line nebulizer treatment feature Alarm sensitivity is adjusted for a 20-minute period in order to reduce nuisance alarms Battery count/discharge on screen Allows clinicians to easily determine

life of battery Circuit type on screen Confidential Sector, MMMM dd, yyyy, Reference 25 Trilogy Series manual addendum The following warning and associated notes are removed in all Trilogy manuals: C-Flex, Bi-Flex and AVAPS are intended for use by adult patients

Confidential Sector, MMMM dd, yyyy, Reference 26 At Philips Respironics were listening carefully to you and working toward solutions that contribute to healthy patients and healthy businesses. Confidential Sector, MMMM dd, yyyy, Reference

27 Confidential Sector, MMMM dd, yyyy, Reference

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